منابع مشابه
Heme synthesis in vitamin B6 and pantothenic acid deficiencies.
Shemin and coworkers (14) showed that the a-carbon and nitrogen atoms of glycine were precursors of specific atoms of the heme molecule. This was substantiated by Muir and Neuberger (5, 6). Other carbon atoms were shown to come from acetate (5-7) or succinate (8). The nature of the intermediate precursors synthesized from these metabolites remained unknown until the structure for urinary porpho...
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Normal human lymphoblasts starved for each of several essential, but not nonessential, amino acids had decreased DNA and RNA synthesis but no change in free intracellular purine nucleotides. The rates of purine nucleotide synthesis via the de novo and salvage pathways were measured by incorporating [14C]formate and [“C]hypoxanthine labels, respectively, into lymphoblasts starved for an amino ac...
متن کاملSynthesis of the Entire Amino Acid Sequence
As described in the preceding paper," the human ƒ¿2-plasmin inhibitor fragment named T11 was found to show high binding activity to plasmin.3) To clarify the structure-activity relationship of this important plasma protein inhibitor fragment, we undertook the synthesis of this fragment and its intermediates by a conventional solution method. In this paper, we describe the synthesis of the hexac...
متن کاملSynthesis and Characterization of Fatty Acid/Amino Acid Self-Assemblies
In this paper, we discuss the synthesis and self-assembling behavior of new copolymers derived from fatty acid/amino acid components, namely dimers of linoleic acid (DLA) and tyrosine derived diphenols containing alkyl ester pendent chains, designated as "R" (DTR). Specific pendent chains were ethyl (E) and hexyl (H). These poly(aliphatic/aromatic-ester-amide)s were further reacted with poly(et...
متن کاملAmino acid synthesis by reversal of the amino acid oxidase reaction.
Although the intermediate formation of an imino acid is consistent with available data, direct experimental evidence for it is still lacking. The reaction in the presence of air proceeds to completion and is essentially irreversible because of reoxidation of the reduced flavoenzyme by molecular oxygen. Previously, the amino acid oxidase reaction has been studied only in the direction of cr-keto...
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ژورنال
عنوان ژورنال: Journal of Inherited Metabolic Disease
سال: 2017
ISSN: 0141-8955,1573-2665
DOI: 10.1007/s10545-017-0063-1